Brain Imaging

The paper presents a novel method for learning normal asymmetry patterns in brain structures. It accurately characterizes normal asymmetries and detects pathological alterations without relying on diseased cases for training. The approach shows promise in improving the identification of neurodegenerative conditions..

NORHA is a novel index for quantifying hippocampal asymmetries in neurodegenerative conditions. It shows promise as a biomarker for detecting unilateral abnormalities, such as hippocampal sclerosis, and correlates positively with the functional cognitive test CDR-SB, indicating its potential in dementia diagnosis.